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Assistant Professor

TEL: 0564-55-7366
E-Mail : (Please replace the "_at_" with @ )
Location: Myoudaiji, South Laboratory Bldg. Room318

Affiliation laboratory >


Research Center of Integrative Molecular Systems, Division of Trans-Hierarchical Molecular Systems
Department of Life and Coordination-Complex Molecular Science, Biomolecular Sensing (Concurrent Position)


2002.3 B.Sc. Engineering, Osaka University
2004.3 M.Sc. Engineering, Osaka University
2007.3 Ph.D Engineering, Osaka University
2007.4-2009.12 IMS Postdoctoral Fellow at Institute for Molecular Science
2010.1-2012.8 CREST Postdoctoral Fellow, Nagoya university
2012. 9- Assistant professor at Institute for Molecular Science
2012.11- Assistant professor at School of Physical Sciences,
The Graduate University for Advanced Studies (adjunct)

Main research themes

(1)Structure-function relationship of proteins
(2)Molecular mechanism of biological rhythm by protein clock

kewords Biological clocks, Biophysics, Relationship between structure and function of proteins

Selected Publications

  1. J. Abe, T.B. Hiyama, A. Mukaiyama, S. Son, T. Mori, S. Saito, M. Osako, J. Wolanin, E. Yamashita, T. Kondo, S. Akiyama, "Atomic scale origins of slowness in the cyanobacterial circadian clock", Science, 349, 312-316 (2015).
  2. A. Mukaiyama, M. Osako, T. Hikima, T. Kondo, S. Akiyama, "A protocol for preparing nucleotide-free KaiC monomer", BIOPHYSICS, 11, 79-84 (2015).
  3. Y. Murayama, A. Mukaiyama, K. Imai, Y. Onoue, A. Tsunoda, A. Nohara, T. Ishida, Y. Maéda, K. Terauchi, T. Kondo, S. Akiyama, "Tracking and visualizing the circadian ticking of the cyanobacterial clock protein KaiC in solution", EMBO J., 30, 68-78 (2011).
  4. A. Mukaiyama, T. Nakamura, K. Makabe, K. Maki, Y. Goto, K. Kuwajima, "Native-state heterogeneity of β2-micloglobulin as revealed by kinetic folding and real-time NMR experiments" , J. Mol. Biol., 425, 255-272 (2013).