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Researchers detail

KOGA, Nobuyasu

Associate Professor

TEL: 0564-55-7379
E-Mail : (Please replace the "_at_" with @ )
Location: Myoudaiji, Main Laboratory Bldg. Room403

Affiliation laboratory >


Exploratory Research Center on Life and Living Systems, Department of Creative Research Protein Design Group

Research Center of Integrative Molecular Systems, Division of Trans-Hierarchical Molecular Systems (Concurrent Position)


2001  B.S. Kobe University
2006  Ph.D.  Kobe University
2003  JSPS Predoctoral Research Fellow
2006  Postdoctoral Fellow, Kobe University
2007  Postdoctoral Fellow, Kyoto Universtiy
2007  JSPS Postdoctoral Fellow for Research Abroad University of Washington
2009  Postdoctoral Fellow, University of Washington
2014  Associate Professor, Institute for Molecular Science
         Associate Professor, The Graduate University for Advanced Studies
2014  JST-PRESTO Researcher (additional post) ( –2017)
2018  Associate Professor, Exploratory Research Center on Life and Living Systems


2013  Young Scientist Award: The 13th Annual Meeting of the Protein Science Society of Japan
2013  Young Scientist Award: The 51th Annual Meeting of the Biophysical Society of Japan
2018  The Morino Foundation for Molecular Science 

Main research themes

De novo Design of Protein Molecule
kewords Protein Design, Protein Folding, Structural Biology
PDF Annual Review : PDF

Selected Publications

  1. Rie Koga, Mami Yamamoto, Takahiro Kosugi, Naohiro Kobayashi, Toshihiko Sugiki, Toshimichi Fujiwara, Nobuyasu Koga, Robust folding of a de novo designed ideal protein even with most of the core mutated to valine. Proc. Natl. Acad. Sci. USA, 117(49), 31149-31156 (2020).
  2. Rie Koga and Nobuyasu Koga, Consistency principle for protein design, Biophys. Physicobiol16, 304-309 (2019).
  3. Nobuyasu Koga, Rie Tatsumi-Koga, Gaohua Liu, Rong Xiao, Thomas B. Acton, Gaetano T. Montelione and David Baker, Principles for designing ideal protein structures, Nature 491(7423), 222-227 (2012).
  4. Yu-Ru Lin, Nobuyasu Koga, Rie Tatsumi-Koga, Gaohua Liu, Amanda F. Clouser, Gaetano T. Montelione, David Baker, Control over overall shape and size in de novo designed proteins, Proc. Natl. Acad. Sci. USA 112(40), E5478-5485 (2015).