Department
Division of Advanced Molecular Science (Life and Coordination-Complex Molecular Science, Biomolecular Functions)
Biography
2009 B.S.The University of Tokyo
2014 Ph. D, University of Tokyo
2014 Postdoctoral Fellow, The University of Tokyo
2015 Assistant Professor, Okazaki Institute for Integrative Bioscience
2018 Assistant Professor, Institute for Molecular Science
2020 Tenure-track Associate Professor, Shizuoka University
2022 Cross-appointment Associate Professor, Institute for Molecular Science
Specialized field
Enzymology, single-molecule biophysics
Main research themes
Engineering of PET hydrolase for plastic recycling and environmental remediation, and engineering of plastic binding domains for detection and quantification of particles
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solid-liquid interfacial reaction, protein-engineering, single-molecule observation |
Selected Publications
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Akihiko Nakamura、Naoya Kobayashi、Nobuyasu Koga、Ryota Iino、「Positive Charge Introduction on the Surface of Thermostabilized PET Hydrolase Facilitates PET Binding and Degradation」ACS Catalysis, vol.11、2021年、P8550-8564
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Akihiko Nakamura、Daiki Ishiwata、Akasit Visootsat、Taku Uchiyama、Kenji Mizutani、Satoshi Kaneko、Takeshi Murata、Kiyohiko Igarashi、Ryota Iino、「Domain architecture divergence leads to functional divergence in binding and catalytic domains of bacterial and fungal cellobiohydrolases」 Journal of Biological Chemistry、vol.295、2020年、P14606～14617
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Akihiko Nakamura、Kei-ichi Okazaki、Tadaomi Furuta、Minoru Sakurai、Ryota Iino、「Processive chitinase is Brownian monorail operated by fast catalysis after peeling rail from crystalline chitin」Nature Communications、vol.9、2018年、P3814
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Akihiko Nakamura、Takuya Ishida、Katsuhiro Kusaka、Taro Yamada、Shinya Fushinobu、Ichiro Tanaka、Satoshi Kaneko、Kazunori Ohta、Hiroaki Tanaka、Koji Inaka、Yoshiki Higuchi、Nobuo Niimura、Masahiro Samejima、Kiyohiko Igarashi、「“Newton’s cradle” proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography」Science Advances vol.1、2015年、pe1500263
