Details of the available projects

Research Center of Integrative Molecular Systems

Project Title: Molecular Origin of 24 h Period in Cyanobacterial Protein Clock
Professor: Shuji AKIYAMA
http://bms.ims.ac.jp/AkiyamaG/

Details of the project:

1) Preparation of cyanobacterial Kai proteins
2) In vitro reconstruction of cyanobacterial protein clock (Kai oscillator)
3) Tracking the circadian ticking of master clock protein (KaiC) in solution

References:

Mol. Cell 2008, 29, 703-716; EMBO J. 2011, 30, 68-78; CMLS 2012 in press (DOI: 10.1007/s00018-012-0919-3)

Required skills:

Experience of either biochemical or biophysical experiment of proteins is requested.