Details of the available projects

Life/Coordination-Complex Molecular Science

Project Title: NMR-based Characterizations of Structures and Interactions of Biological Macromolecules
Professor: Koichi KATO
http://groups.ims.ac.jp/organization/kkato_g/index_e.html

Details of the project:

1) Preparation of proteins, oligosaccharides, and/or glycoconjugates by chemical and/or molecular biology methods.
2) Chemical modification of the biomacromolecules for NMR studies.
3) NMR analyses of structure, dynamics, and/or interactions of the biomacromolecules.

References:

Angew. Chem. Int. Ed. 2014, 53, 10941. Sci. Rep. 2014, 4, 7322. Nature Struct. Mol. Biol. 2015, DOI: 10.1038/nsmb.2954.

Required skills:

Experience of analytical chemistry, biochemistry, organic chemistry, and/or molecular biology experiments is preferable.