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Researchers detail

Assistant Professor

KOSUGI, Takahiro

TEL: 0564-55-7379
Mail: takahirokosugi_at_ims.ac.jp (Please replace the "_at_" with @ )
Affiliation laboratory:
Location: Myoudaiji, Laboratory Bldg. Room404

Department

Research Center of Integrative Molecular SystemsDivision of Trans-Hierarchical Molecular Systems

Exploratory Research Center on Life and Living Systems, Department of Creative Research Protein Design Group  (adjunct)

Biography

2005 B.S. Kyoto University 
2012 Ph.D.  Kyoto University
2008 JSPS Fellow (DC2)   
2012 JSPS Fellow for Research Abroad    
2014 Postdoctral Fellow, University of Washington   
2015 Assistant Professor, Institute for Molecular Science  

Awards

2013 Best Presentation Award at the 41th Symposium of Structure-Activity Relationships        
2014 Best Presentation Award at the Anuual Meeting of the Japan Society for Molecular Science      

Specialized field

Biophysics, Theoretical Chemistry

Main research themes

Study Protein Functions by Designing Proteins
kewords Protein Design, Theoretical Chemistry, Molecular Simulation, Biochemistry, Directed Evolution

Selected Publications

  1. QM/MM Reweighting Free Energy SCF for Geometry Optimization on
    Extensive Free Energy Surface of Enzymatic Reaction.
    Takahiro Kosugi and Shigehiko Hayashi. J. Chem. Theory Comput. 2012, 8, 322-334.
  2. Crucial Role of Protein Flexibility in Formation of a Stable Reaction Transition State in an a-amylase Catalysis.
    Takahiro Kosugi and Shigehiko Hayashi. J. Am. Chem. Soc. 2012, 134, 7045-7055.