Department
Division of Advanced Molecular Science
(Life and Coordination-Complex Molecular Science, Biomolecular Functions)
Biography
2003 Junior Research Associate, RIKEN
2006 2007 IMS fellow, Institute for Molecular Science, National Institute of Natural Sciences
2007-2010 Postdoctoral researcher, JSPS
2010-2013 Research Assistant Professor, Okazaki Institute for Integrative Bioscience, National Institute of Natural Sciences
2013-2022 Assistant Professor, Graduate School of Life Science, University of Hyogo
2006-2025 Visiting Scientist, RIKEN SPring-8 Center
2022-2025 Associate Professor, Chemistry and Materials Engineering Program, Graduate School of Engineering, Nagasaki University
2023-Present LINXS Fellow, Chemistry of Life, LINXS Institute of Advanced Neutron and X-ray Science
2024 Associate Professor (Cross Appointment), Institute for Molecular Science
2025-Present Part-time Lecture, Nagasaki University
2025-Present Professor, Graduate School of Science, Department of Chemistry, Osaka Metropolitan University
2025-Present Professor (Cross Appointment), Institute for Molecular Science
Awards
2008 Best Poster Prize, 4th International conference on metals and genetics
2010 Yamamura Fellow, Fumi Yamamura Memorial Foundation for Female Natural Scientists, Chuo Mitsui Trust and Banking
2011 Poster award, the Crystallographic Society of Japan
2012 Presentation award, the 92th CSJ Annual Meeting, the Chemical Society of Japan
2012 Shiseido Female Researcher Science Grant, SHISEIDO Company, Limited
2018 Excellent Research Award, The Japanese BioIron Society
Main research themes
Molecular Science of Bio-metal Dynamics: Understanding and regulation of the strategies of metal utilization in living things
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Metal transporters, metal chaperones, metal ion transfer mechanisms through protein-protein interactions, functional analysis using human intestinal cells |
Selected Publications
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Menega Ganasen, Hiromi Togashi, Hanae Takeda, Honami Asakura, Takehiko Tosha, Keitaro Yamashita, Kunio Hirata, Yuko Nariai, Takeshi Urano, Xiaojing Yuan, Iqbal Hamza, A. Grant Mauk, Yoshitsugu Shiro, Hiroshi Sugimoto, Hitomi Sawai (2018) “Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate” Communications Biology, 1, 120. doi: 10.1038/s42003-018-0121-8
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Gareth S. A. Wright, Akane Saeki, Takaaki Hikima, Yoko Nishizono, Tamao Hisano, Misaki Kamaya, Kohei Nukina, Hideo Nishitani, Hiro Nakamura, Masaki Yamamoto, Svetlana V. Antonyuk, S. Samar Hasnain, Yoshitsugu Shiro, Hitomi Sawai (2018) “Architecture of the complete oxygen-sensing FixL-FixJ two-component signal transduction system” Science Signaling, 11, eaaq0825. doi: 10.1126/scisignal.aaq0825
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Megumi Nishinaga, Hiroshi Sugimoto, Yudau Nishitani, Seina Nagai, Satoru Nagatoishi, Norifumi Muraki, Takehiko Tosha, Kouhei Tsumoto, Shigetoshi Aono, Yoshitsugu Shiro, Hitomi Sawai (2021) “Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival” Communications Biology, 4, 467. doi: 10.1038/s42003-021-01987-5
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『生命金属ダイナミクス：生体内における金属の挙動と制御』第4章 維持─分子─ 第2節 生体鉄の分子科学と細胞生物学（城 宜嗣、澤井 仁美、當舎 武彦）、エヌ・ティー・エス出版、ISBN: 9784860437060
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『ヘムタンパク質の科学：生理機能の理解とその展開に向けて』第3章 情報交換：情報伝達に関与するヘムタンパク質 第2節 シグナル分子として機能するヘム（澤井 仁美）／第4章 ヘム輸送とヘム代謝 第3節 金属イオンの取り込みに関与するヘム含有酵素（澤井 仁美）、エヌ・ティー・エス出版、ISBN: 9784860437787
