Biography

1999 Dept. of Chemistry, School of Science, Tokyo Institute of Technology
2003 Graduate, Yokohama City University
2005 Department of Molecular Engineering, Graduate School of Engineering, Kyoto University
2008 Researcher, Graduate School of Engineering, Kyoto University
2011 Postdoctoral Researcher, Quantitative Biology Center (QBiC), RIKEN
2017 Research scientist, Quantitative Biology Center (QBiC), RIKEN
2018 Research scientist, Center for Biosystems Dynamics Research (BDR), RIKEN
2020 Project Associate Professor, Graduate School of Science, Tokyo Metropolitan University
2024 Project Associate Professor, Okazaki Collaborative Platform, Core for Spin Life Sciences (Spin-L), National Institutes of Natural Sciences

Main research themes

Biomolecular Science Based on In Situ Observation by Magnetic Resonance

In-cell NMR, Spin life science, Magnetic resonance measurements, Structural dynamics of proteins

Selected Publications

1. Masaomi Ikari, Hiromasa Yagi, Takuma Kasai, Kohsuke Inomata, Masahiro Ito, Kae Higuchi, Natsuko Matsuda, Yutaka Ito, and Takanori Kigawa., “Direc Observation of Membrane-Associated H-Ras in the Native Cellular Environment by In-Cell ¹⁹F-NMR Spectroscopy”, JACS Au, 3, 1658-1669, (2023)
2. Kohsuke Inomata, Hajime Kamoshida, Masaomi Ikari, Yutaka Ito, and Takanori Kigawa., “Impact of cellular health conditions on the protein folding state in mammalian cells”, Chemical Communications, 53, 11245-11248, (2017)
3. Yuya Hikone, Go Hirai, Masaki Mishima, Kohsuke Inomata, Teppei Ikeya, Souichiro Arai, Masahiro Shirakawa, Mikiko Sodeoka, and Yutaka Ito., “A new carbamidemiethy-linked lanthanoid chelating tag for PCS NMR spectroscopy of proteins in living HeLa cells”, Journal of Biomolecular NMR, 66, 99-110, (2016)
4. Jens Danielsson, Kohsuke Inomata, Shihei Murayama, Hidehito Tochio, Lisa Lang, Masahiro Shirakawa, and Mikael Oliveberg., “Prunning the ALS-Associeted Protein SOD1 for in-cell NMR”, Journal of American Chemical Society, 135, 10266-10269, (2013)
5. Kohsuke Inomata, Ayako Ohno, Hidehito Tochio, Shin Isogai, Takeshi Tenno, Ikuhiko Nakase, Toshihide Takeuchi, Shiro Futaki, Yutaka Ito, Hidekazu Hiroaki, and Masahiro Shirakawa., “High-resolution multi-dimensional NMR spectroscopy of proteins in human cells”, Nature, 458, 106-109, (2009)