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分子研研究会(3/15-16)

演 題 「New Frontier in Protein Design & Engineering」
日 時 2019年03月15日(金) 13:30 より 2019年03月16日(土) 15:00 まで
場 所

分子科学研究所 研究棟201号室

概 要

program
March 15, 2019(Fri)

13:30-13:50 Opening Remarks and Introduction
Ryoichi Arai (Shinshu Univ.) & 
Nobuyasu Koga (IMS, ExCELLS)
13:50-14:25 Osami Shoji (Nagoya Univ.)
“Hydroxylation of Nonnative Substrates Catalyzed by Cytochrome P450BM3 Facilitated by Decoy Molecules”
14:25-14:50 Daisuike Matsui (Toyama Prefectural Univ.)
“Rational identification of aggregation hotspots based on secondary structure and amino acid hydrophobicity”
14:50-15:15 Naoya Kobayashi (ExCELLS)
“Cumulative thermostabilization of beta-glucosidase with structure-based sequence profile information”
15:15-15:35 coffee break
Special Lecture
15:35-16:20

Michael Hecht (Princeton Univ.)

“Sustaining Life with Genes and Proteins Designed ‘From Scratch’ ”
16:20-16:35  coffee break
16:35-17:00

Shintaro Minami (ExCELLS)

“Design of new fold proteins yet-unexplored in nature"

17:00-17:35

Tomoaki Matsuura (Osaka Univ.)

“Engineering and characterizing membrane proteins using artificial cells”

17:35-18:00

Naohiro Terasaka (Univ. of Tokyo) 

“Directed evolution of bacterial protein cages to package their own mRNA”

March 16, 2019(Sat)
9:30-9:55

Daisuke Kuroda (Univ. of Tokyo)

“Exploring antibody designability through physicochemical analyses, mutagenesis and computations”
9:55-10:20

Takao Arimori (Osaka Univ.)

“Development of an artificially designed antibody fragment “Fv-clasp”

10:20-10:55

Munehito Arai (Univ. of Tokyo)

“Experimental and theoretical design of enzymes and binding proteins”

 10:55-11:15  coffee break
11:15-11:40

Yuta Shinohara (RIKEN)

“Design principles of temperature-compensated phosphorylation in the circadian clock”

11:40-12:15

Satoshi Akanuma (Waseda Univ.)

“Protein engineering experiments to explore the evolution of early life”

12:15-13:15   lunch
13:15-13:50

Koki Makabe (Yamagata Univ.)

“Folding and Design of the Peptide Self-Assembly Mimics, PSAMs”

13:50-14:25

Paola Laurino (OIST)

“A journey from an ancient finger print of Rossmann fold enzymes to cofactor engineering”

14:25-15:00

Mitsuo Umetsu (Tohoku Univ.)

Can proteins be engineered to generate a desired function from slim library ?”

 

その他

準備の都合上、氏名、所属、参加日を下記申込先までメールにてご連絡下さい。*_at_は@に変換して下さい。
申込先:hiroko_at_ims.ac.jp*(分子科学研究所 鈴木博子)
問合せ先:rarai_at_shinshu-u.ac.jp*信州大学 新井亮一

nkoga_at_ims.ac.jp*(分子科学研究所 古賀信康)
締め切り:2019年3月4日(月)
Organizer: Ryoichi Arai (Shinshu Univ.) , Nobuyasu Koga (IMS, ExCELLS)